Molecular encapsulation and reactivity with assembled baskets in | 33148
Organic Chemistry: Current Research

Organic Chemistry: Current Research
Open Access

ISSN: 2161-0401

+44 1478 350008

Molecular encapsulation and reactivity with assembled baskets in water

International Conference on Organic Chemistry

August 10-11, 2016 Las Vegas, Nevada, USA

Jovica Badjic

The Ohio State University, USA

Scientific Tracks Abstracts: Organic Chem Curr Res

Abstract :

The entrapment of guest compounds with artificial hosts allows for controlling local environment and properties of a variety of analytes. In particular, one can use molecular encapsulation for stabilizing reactive intermediates, promoting chemical reactions and modulating conformational dynamics of guests. We recently developed so-called gated molecular baskets for regulating the activation energy (�?�?Gâ�?¡ in/out) characterizing the ingress/egress of molecules and thereby chemical reactivity. Interestingly, molecular baskets were additionally found to assemble into stimuli-responsive vesicles in an aqueous environment. These nanostructured materials are capable of trapping nerve agents in water in an allosteric manner. The lecture will focus on presenting our recent efforts toward understanding working mechanisms baskets in controlling the recognition of various guests. I will also discuss the utility of assembled baskets for C-H activation of small hydrocarbons in water.

Biography :

Jovica Badjic completed his PhD in 2001 in the area of Organic Chemistry and Post-doctoral studies from UCLA in 2003. He is currently Professor of Chemistry at the Ohio State University. He has published in the area of supramolecular chemistry and catalysis.