ISSN: 2376-0419
+44 1300 500008
Richard I Licayan1, Romeo M Del Rosario1, Nenita D Palmes2 and Aisle Janne B Dagpin1
Posters-Accepted Abstracts: J Pharma Care Health Sys
Hiptage benghalensis, Antigonon leptopus, Macroptillium atropurpureum, and Dioscorea bulbifera L. are herbal weeds that have
been used by traditional healers in rural communities in the Philippines as medicine. In this study, the basic pharmacological
components of the crude secondary metabolites extracted from the four herbal weeds and their in vitro antioxidant properties was
investigated to provide baseline data for the possible development of these metabolites in pharmaceutical products. Qualitative
screening of the secondary metabolites showed that alkaloids, tannins, saponins, steroids, and flavonoids were present in their leaf
extracts. All of the plant extracts showed varied antioxidant activity. The greatest DPPH radical scavenging activity was observed in
H. begnhalensis (84.64%), followed by A. leptopus (68.21%), M. atropurpureum (26.62%), and D. bulbifera L. (19.04%). The FRAP
assay revealed that H. benghalensis had the highest antioxidant activity (8.32 mg/g) while ABTS assay showed that M. atropurpureum
had the strongest scavenging ability of free radicals (0.0842 mg Trolox/g). The total flavonoid content (TFC) analysis showed that D.
bulbifera L. had the highest TFC (420.35 mg quercetin per gram-dried material). The total phenolic content (TPC) of the four herbal
weeds showed large variations, between 26.56±0.160 and 55.91±0.087 mg GAE/g dried material. The plant leaf extracts arranged in
increasing values of TPC are H. benghalensis (26.565)