Accepted Abstracts: Biochem & Pharmacol
The increasing worldwide incidence of diabetes mellitus in adults constitutes a global public health burden. It is predicted that by 2030, India, China and the United States will have the largest number of people with diabetes. By definition, diabetes mellitus is categorized as a metabolic disease characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both. The vast majority of cases of diabetes fall into two broad etiopathogenetic categories. The first category, type 1 diabetes, the cause is an absolute deficiency of insulin secretion. While the second type is much more prevalent category, called as type 2 diabetes, the cause is a combination of resistance to insulin action and an inadequate compensatory insulin-secretory response. Despite the great interest in the development of new drugs to prevent the burden of complications associated with this disease and the raised interest in the scientific community to evaluate either raw or isolated natural products in experimental studies, few of them were tested in humans. This review is a contribution to the understanding of ethnopharmacology of plants having hypoglycemic activity and its contribution to the elaboration of new treatment of diabetes mellitus.
Mohamed Eddouks is Professor at Moulay Ismail University, Morocco. After his post-doctoral fellowship at Department of Physiology, Faculty of Medicine of Montreal, Canada, he is working for the last 12 years on medicinal plants. His contribution to this field includes 3 international books and more than 70 peer-reviewed articles and book chapters of international repute. His is serving as editorial member of some prestigious journals. He has been the Dean of Polydisciplinary Faculty of Errachidia from 2008 to 2012.