Journal of Developing Drugs
Open Access
ISSN: 2329-6631
ISSN: 2329-6631
Nutan Kaushik and Daya Bhardwaj
The Energy and Resources Institute (TERI), India
Posters-Accepted Abstracts: J Develop Drugs
According to World Health Organization��?s (WHO��?s) survey there is increasing demand of traditional medicines all over the world. Such increase in the popularity of herbal products is also associated with the problems of adulteration, safety and efficacy issues. Review of literature of over last decade reveals that HPLC and hyphenated techniques are the most widely used techniques for the quality control of medicinal plants. Different HPLC methods have been developed for quality control evaluation process of herbal medicines. The level of methods varies from simple qualitative comparison of HPLC chromatograms with the available standards of marker compounds to the complex quantitative generation and interpretation of data obtained by advanced hyphenated HPLC methods. Combining a chromatographic separation system with a spectroscopic system on-line or with a spectroscopic detector in order to obtain structural information on the analytes present in a sample has become the most important approach for the identification and/or confirmation of the identity of target and unknown chemical compounds. These techniques not only gives a better fingerprint picture but smartly spells out each and every components in either the raw materials or in the most complex formulations of medicinal plants. Chromatogram and spectrum generated by these methods could provide efficient separation of metabolites and valuable structure information .Various hyphenated procedures have been reported, such as HPLC-MS, HPLCDAD- MS and HPLC-NMR. In this paper advancements in the field of HPLC fingerprinting technique in last decade will be presented.
Email: kaushikn2015@gmail.com