Organic Chemistry: Current Research
Open Access

Green bivariate calibration method vs. HPLC: A study on simultaneous determination of binary components in pharmaceutical formulations

2^nd International Conference on Past and Present Research Systems of Green Chemistry

September 14-16, 2015 Orlando, USA

Anas Lataifeh

Tafial Technical University, Jordan

Posters-Accepted Abstracts: Organic Chem Curr Res

Abstract :

Developing a fast, reliable and precise analytical method is the objective of current analytical methods. Miniaturization and reduction of the consumption of organic chemicals is a second objective. In our group, we have challenged these requirements by developing the bivarite calibration method to quantify binary components in pharmaceutical preparations by UV-vis spectrophotometer. The bivariate method requires direct UV-vis acquisition, organic solvent less for sample preparation and short time for data treatment. The quality of the bivarite method results and the environmental friendliness of the method compared to HPLC method meet the key components of green analytical method. The HPLC methods are the current method of choice in routine drug monitoring, though it requires lengthy procedure and use of organic solvent. The proofs of concept presented here demonstrate the usefulness of the bivarite methodology and how potentially in future, might be a substitute for non-green, laborious HPLC methods.

Biography :

Email: lataifeh@ttu.edu.jo