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Exploring host-pathogen interactions with quantitative proteomics | 20775
Journal of Proteomics & Bioinformatics

Journal of Proteomics & Bioinformatics
Open Access

ISSN: 0974-276X

+44 1223 790975

Exploring host-pathogen interactions with quantitative proteomics


2nd International Conference on Proteomics & Bioinformatics

July 2-4, 2012 Embassy Suites Las Vegas, USA

Leonard J. Foster

Scientific Tracks Abstracts: J Proteomics Bioinform

Abstract :

Salmonella is an facultative intracellular pathogen that is a primary cause of gastroenteritis around the world. We develop and apply a variety of quantitative proteomic approaches to understand the host-pathogen interactions involving this bacteria. I will discuss how we have approached the identification of type 3 secreted proteins from the bacteria, which host proteins those effectors target and how those effectors regulate intracellular signalling and the composition of intracellular compartments, including lipid rafts. I will also discuss a novel method we have developed for monitoring the interactome of a cell and how the network of protein interactions responds to extracellular stimuli.

Biography :

Leonard Foster completed his Ph.D at the University of Toronto when he was 26 and went from there to the University of Southern Denmark to pursue post-doctoral studies with Prof. Matthias Mann. In 2005 he started his current position at the University of British Columbia, where he is now an associate professor of biochemistry and molecular biology and the director of their proteomics core facility. In the last seven years he has published more than 60 papers and he holds the Canada Research Chair in Quantitative Proteomics

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