Drug Designing: Open Access
Open Access

Evaluation of the role of ischemia modified albumin as a new biochemical marker for differentiation between ischemic and haemorrhagic stroke

2^nd International Conference and Expo on Drug Discovery & Designing

October 27-29, 2016 Rome, Italy

Nany Hassan Abu Al-Makarim El Gayar

Alexandria University, Egypt

Posters & Accepted Abstracts: Drug Des

Abstract :

Objective: To evaluate the role of the detection of ischemia modified albumin (IMA) level in the differentiation between ischemic and haemorrhagic cerebrovascular stroke. Materials & Methods: 60 elderly persons classified into three groups, 25 patients diagnosed with cerebral infarction, 15 patients diagnosed with cerebral haemorrhage, and 20 elderly healthy persons with matched age as control were enrolled in the study. IMA was measured using the available chemical method and computerized tomography (CT) was done for diagnosis of brain lesions. Results: IMA was significantly higher in patient group than control group. There was positive significant correlation between age, albumin with IMA, (P=0.000 and 0.037 respectively). However there was no statistical significant difference between sex and diagnosis cross tabulation (0.51). It was found that, IMA was statistically higher in infarction group than haemorrhage group (P=0.000) and IMD index was statistically higher in infarction group than haemorrhage group (P=0.013). Conclusion: Our investigation in elderly patients suggests that IMA assay is a sensitive marker for early detection ischemic and haemorrhage stroke.

Biography :

Email: mohamed.eddouks@laposte.net