Journal of Cell Science & Therapy
Open Access

Epigenetic marker for the diagnosis and treatment for Korean asthma patients in Korean differentiationsyndrome category: Pilot study

11^th World Congress on Cell & Tissue Science

May 09-10, 2018 Tokyo, Japan

Ju Yeon Ban, Seul-A Jin, Sang Wook Kang and Su Kang Kim

Dankook University, Republic of Korea
Catholic Kwandong University, Republic of Korea

Posters & Accepted Abstracts: J Cell Sci Ther

Abstract :

The present study shows a novel epigenetic marker for diagnosis and treatment for Korean asthma patients in Korean differentiation syndrome category. We recruited 62 patients with asthma from respiratory medicine department in Kyung Hee University Korean Medicine Hospital, Pusan National University Korean Medicine Hospital, Daejeon University Dunsan Korean Medicine Hospital and Semyung University Korean Medicine Hospital. They are classified by symptom diagnosis and questionnaire and their DNA were collected. Epigenetic analysis was performed using agilent sureselect human methylsequencing. In results, total of 8 sites in exon region in MDGA1 gene was considered to be closely related to differentiationsyndrome category in Korean asthma patients. The gene that contains the region MDGA1 could be regarded for differentiationsyndrome category in Korean asthma patients as an epigenetic candidate marker. jyban@dankook.ac.kr