Clinical & Experimental Cardiology
Open Access
ISSN: 2155-9880
ISSN: 2155-9880
Charan Teja Reddy Yerasi
Medstar Washington Hospital Center, USA
Posters-Accepted Abstracts: J Clin Exp Cardiolog
Background: Cardiac MRI plays a promising role in the diagnosis of Takotsubo Cardiomyopathy (TC). Evidence on impact of late gadolinium enhancement (LGE) by Cardiac MRi, on in-hospital outcomes is lacking. We sought to do a retrospective study evaluating the effect of LGE. Methods: We identified 39 TC patients who had a Cardiac MRI done in the acute phase. Patients were allotted into two groups: 1.LGE present (10) 2.LGE absent (29). All presented with: 1) acute cardiac symptoms, 2) a characteristic left ventricular contraction pattern and 3) no major CAD. Baseline characteristics are recorded. The occurrence of hospital mortality, length of stay, and cardiac complications were analyzed. Results: Mean age was 67�?±12 yrs. No significant differences in baseline characteristics are noted. Median time to MRI was 2 days [1-3]. Average EF on initial Echo was 38.5�?±14% in LGE group and 38�?±9% in without LGE group (p=0.96) with improvement to 16�?±1% and 12�?±2% (p=0.04) respectively. No In-hospital mortality was noted. Outcomes on two groups respectively, are as follows: Median Hospital stay was 3 [3-4] and 4[3-6.5] (p=0.09), Median CCU days were 2.5[1-4] and 2[1-3] (p=0.69), inotrope requirement was in 10% v/s 13%, (p=0.75) and Mechanical ventilation was 10% v/s 4%, (p=0.41), new onset arrhythmias were found in 0% v/s 7%, (p=0.39). Conclusions: Significant improvement of EF was noted in Takotsubo patients, in both LGE and no LGE groups. LGE by Cardiac MRI did not show any difference in the clinical outcomes of patients. However this study was limited by its smaller sample size. Further studies with larger sample size should be done to validate the results.