Kristine I. Alvaro
Univeristy of the Philippines Manila-Philippine General Hospital Manila, Philippines
Posters & Accepted Abstracts: Gynecol Obstet
Cervical cancer is an important cause of mortality among women. Adenocarcinoma is a rare form of cervical cancer with the clear cell morphology contributing to a certain percentage of the total. Due to its rarity, clinical dilemmas on screening, diagnosis, and treatment are abloom in practice. This paper aims to present two cases of early-stage disease clear cell carcinoma of the cervix with almost similar manifestations but managed differently. This paper also aims to review current existing literature about clear cell carcinoma and what we presently know of its risk factors, presentation, management and prognosis. Two cases of clear cell carcinoma of the cervix in its early stages are presented and discussed in light of recent literature. The first is a case of a 36-year old gravida 1 para 1 (1001) who has clinical stage 1B1 cancer and was managed by radical hysterectomy with complete staging and adjuvant chemoradiation. The second case is in a 45-year old, gravida 6 para 5 (4115), stage IB1 who also underwent the same procedure but did not receive adjuvant therapy. Both patients were in remission in the years of follow-up. The risk factors, presentation, and management of early-stage clear cell cervical cancer may differ from the usual cervical cancer. The future of fertility-sparing surgery is described in this paper as it has been found to provide a plausible new aspect in management of selected patients with clear cell cancer of the cervix in the early stage.