Demonstrating the polyvalent properties of cannabinoid compounds | 30361
Journal of Pharmaceutical Care & Health Systems

Journal of Pharmaceutical Care & Health Systems
Open Access

ISSN: 2376-0419

+44 1300 500008

Demonstrating the polyvalent properties of cannabinoid compounds for the treatment of Alzheimer’s disease

Pharmaceutical Summit and Expo

October 08-10, 2015 New Delhi, India

T K Mohd Rayees

Deccan School of Pharmacy, India

Posters-Accepted Abstracts: J Pharma Care Health Sys

Abstract :

The last two decades of research have brought a tremendous improvement in knowledge of the endocannabinoid system components and functions under physiological and pathological conditions. The endocannabinoid system is composed by a number of cannabinoid receptors, including the well-characterized CB1 and CB2 receptors, with their endogenous ligands and the enzymes related to the synthesis and degradation of these endocannabinoid compounds. Endocannabinoid signaling has been demonstrated to modulate numerous concomitant pathological processes, including neuro-inflammation, excite-toxicity, mitochondrial dysfunction, and oxidative stress. Targeting the endogenous cannabinoid system has emerged as a potential therapeutic approach to treat â�?¢ Effect of cannabinoids on A�?² â�?¢ Cannabinoids on tau hyper-phosphorylation â�?¢ Anti-inflammatory properties of cannabinoids â�?¢ Cannabinoid actions on mitochondrial activity: Oxidative stress and energy metabolism â�?¢ Cannabinoids modulate neurotransmission â�?¢ Other effects of cannabinoids in AD Conclusion: In conclusion, in light of the polyvalent properties for the treatment of AD and the limited side effects exhibited by these compounds, progress toward a clinical trial to test the capacity of cannabinoids to curb this neurodegenerative disease seems to be fully justified.

Biography :

T K Mohd Rayees is an Undergraduate student of Deccan School of Pharmacy pursuing Doctor of Pharmacy (PharmD D V/VI), affiliated to Jawaharlal Nehru Technological University.