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Current therapies for refractory angina and potential effects of | 57574
Clinical & Experimental Cardiology

Clinical & Experimental Cardiology
Open Access

ISSN: 2155-9880

Current therapies for refractory angina and potential effects of internal mammary artery occlusion


Joint Event on 3rd International Conference on Cardiovascular Medicine and Cardiac Surgery & 26th Annual Conference on Clinical & Medical Case Reports in Cardiology

July 05-06, 2018 | Berlin, Germany

Marco Piciche

San Bortolo Hospital, Italy

Keynote: J Clin Exp Cardiolog

Abstract :

No one knows the true incidence of refractory angina, but it is generally agreed that there are thousands new cases annually. The incidence will presumably increase with the increase of average age. Patients suffering from refractory angina are known as no-option, because they are not amenable to coronary artery bypass grafting or percutaneous coronary interventions. The main reason to be unamenable to conventional revascularization techniques is a diffuse coronary disease, and secondarily comorbidities. Several alternative methods have been advocated, such as stem cell therapy, external counter-pulsation, laser transmyocardial revascularization sympathectomy, partial occlusion of the coronary sinus, shock wave myocardial revascularization. The internal mammary artery (IMAs) has the potential for developing collateral branches under some circumstances. This was the basis for an old operation performed in the 1940s, i.e. the tunnellization of the IMAs in to the left ventricle free wall.
Recent Publications
1. Iwanski J, Knapp S M, Avery R, Oliva I, Wong R K, Runyan R B, et al. (2017) Clinical outcomes meta-analysis: measuring subendocardial perfusion and efficacy of transmyocardial laser revascularization with nuclear imaging. Journal of Cardiothoracic Surgery 12(1):37.
2. Holland L C, Navaratnarajah M and Taggart D P (2016) Does surgical sympathectomy improve clinical outcomes in patients with refractory angina pectoris? Interactive Cardiovascular and Thoracic Surgery 22(4):488-92.
3. Giannini F, Baldetti L, Ielasi A, Ruparelia N, Ponticelli F, Latib A, et al. (2017) First Experience with the coronary sinus reducer system for the management of refractory angina in patients without obstructive coronary artery disease. JACC: Cardiovascular Interventions 10(18):1901-1903.
4. Myojo M, Ando J, Uehara M, Daimon M, Watanabe M and Komuro I (2017) Feasibility of extracorporeal shock wave myocardial revascularization therapy for post-acute myocardial infarction patients and refractory angina pectoris patients. International Heart Journal 58(2):185-190.
5. Picich�?¨ M (2012) The history of myocardial revascularization before the advent of cardiopulmonary bypass. Dawn and Evolution of Cardiac Procedures 65â�?�?77, ISBN: 978-88-470-2400-7.

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