Abd El Hamid Ismael, Ihab El-Sayed, Mansour Mostafa, Mostafa Mokarrab, Abdel Aleem Ali, Haitham Sabry and Amr Yosry
Al-Azhar University, Egypt
Posters & Accepted Abstracts: J Clin Exp Cardiolog
Background: Accurate risk stratification for contrast-induced nephropathy (CIN) is important for patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PPCI). Aim: Aim of this study is to compare between different risk scores for predicting contrast induced nephropathy and short outcome after primary percutaneous coronary intervention in patients with ST elevation myocardial infarction. Material & Methods: We prospectively enrolled 100 patients with STEMI undergoing PPCI. Mehran; Gao; Chen; age, serum creatinine, or glomerular filtration rate, and ejection fraction (ACEF or AGEF); and Global Registry for Acute Coronary Events risk scores were calculated for each patient. The prognostic accuracy of the six scores for CIN, and in-hospital death and major adverse clinical events (MACEs) was assessed. CIN was defined as an increase of 25% or 0.5 mg/dL serum creatinine within 2-3 days after PCI. The data was analyzed using Chi-square test using SPSS software. Results: All risk scores had relatively good predictive values for CIN (AUC: 0.671 to 0.829) and performed well for prediction of in-hospital death (0.838 to 0.973), MACEs (0.815 to 0.926). The Gao and Mehran risk scores had better predictive accuracy for CIN. While GRACE and Mehran risk scores had better predictive accuracy for in-hospital MACEs and death. Conclusion: Risk scores for predicting CIN perform well in stratifying the risk of CIN and in-hospital death or MACEs in patients with STEMI undergoing PPCI. The Gao and Mehran risk scores appear to have greater prognostic value.