Andres Diaz, Juan Jose Diaztagle, Alejandro Olaya, Gui- llermo Mora, Ignacio Lopez-Lima, Carolina Ayala, Gina Polo, Nestor Galizio and Josep Brugada
Fundacion Universitaria de Ciencias de la Salud, Colombia
Hospital San Jose, Colombia
Fundacion Santa Fe de Bogota, Colombia
Universidad Nacional de Colombia, Colombia
Hospital Dr. Guillermo Rawson, Argentina
Universidade de Sao Paulo, Brazil
Hospital Universitario Fundacion Favaloro, Argentina
Hospital Clinic de Barcelona, Spain
Universitat de Barcelona, Spain
Scientific Tracks Abstracts: J Clin Exp Cardiolog
Reactivation processes of Chagas Disease (CD) have been poorly investigated. Eighty-two CD seropositive patients (64.6% females; age=58.9±9.9) without ischemic heart disease nor condi- tions that cause myocardial fibrosis and dilation were considered. Late gadolinium enhancement (LGE) and T2-weighted magnetic resonance imaging of edema were obtained and represented using a 17-segment model. Patients were divided into three groups according to the left ventricular (LV) ejection fraction (EF) as: G1 (EF>60%; n=37), G2 (35%>EF<60%; n=33) and G3 (EF<35%; n=12). Comparisons were performed by the Fisher or ANOVA tests. A Spearmans correlation was also performed. Edema was observed in 8 (9.8%) patients; 2 (5.4%) of G1, 4 (12.1%) of G2 and 2 (16.7%) of G3. It was observed at the basal inferolateral segment in 7 (87.5%) cases. LGE was observed in 48 (58.5%) patients; 16 (43.2%) of G1, 21 (63.6%) of G2 and 11 (91.7%) of G3 (p<0.05). It was predominantly observed in the basal segments in 35 (72.9%) patients, and in the apical seg- ments in 21 (43.7%), with midwall (85.4%;n=41), and subendocardial (56.3%;n=27) distribution (Fig. 1A). Subendocardial lesions were observed only in patients with LVEF <30%. There was no involvement of the mid segments with a LVEF >35% (p<0.05). Deteriorations of the LV and RV systolic functions were positively correlated (rs=0.69; p<0.05) without evidence of LGE in the RV. Edema can be found in patients with chronic chagasic cardiomyopathy.
Andrés Díaz, MD, cardiologist, electrophysiologist, master in clinical electrophysiology and cardiac stimulation. PhD candidate in medicine and translational research from the University of Barcelona. He has published papers in reputed journals of cardiology and has been serving as an editorial board member of repute scientific journals.