Garba S, Shoge M and Labaran S
Nigerian Defense Academy, Nigeria
Posters & Accepted Abstracts: J Pharma Care Health Sys
The antimicrobial activity of 1,2-benzenedicarboxylic acid, butyldecyl ester isolated from Acacia nilotica was determined using standard methods. The compound was isolated by directing the fractionation of ethyl acetate extract of the air dried seeds and pod with microbial sensitivity test. The results of the antibacterial screening showed that the ethyl acetate extract of Acacia nilotica Linn exhibited the highest activities against the test microbes with zones of inhibition diameter ranging from 27-32 mm against Salmonela Typhi, Escherichia coli, Streptococcus feacalis, Staphylococcus aureus, Candida krusei and Shigella dysentriae. The structure of the compound was identified from 13CNMR, 1HNMR, IR and GC-MS spectral data. The isolation, structural elucidation, NMR spectral assignment and bioactivities are reported.
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