Antifungal activity of Stachys acerosa Boiss extract on Candida s | 44075
Journal of Pharmaceutical Care & Health Systems

Journal of Pharmaceutical Care & Health Systems
Open Access

ISSN: 2376-0419

+44 1300 500008

Antifungal activity of Stachys acerosa Boiss extract on Candida species isolated from Oral Candidiasis

11th World Congress on Pharmaceutical sciences

September 28-29, 2018 | Montreal, Canada

Nasrin Amirrajab, Sadegh Tehrani, Yusef Yalaly, Ehsan Ahmadi, Sedigheh Yusef Naanaie and Batool Sadeghi-Nejad

Ahvaz Jundishapur University of Medical Sciences, Iran

Posters & Accepted Abstracts: J Pharma Care Health Sys

Abstract :

Background and Purpose: Dental caries is one of the most important global health problems. Yeasts, including Candida species, are also found in the oral cavity as a normal flora. An alternative approach to overcoming these issues may be the use of natural and phytochemical antimicrobials. The Middle East is exclusively used for medicinal plants used to treat diseases and infections in traditional medicine for thousands of years (1-3). On the other hand, the most of these synthetic antimicrobial products have some adverse effects, which make them less popular. Hence, the aim of this study was to evaluate the antifungal properties of Stachys acerosa extracts against Candia species. Materials and Methods: In this study, we assessed the activities of Stachys acerosa leaf extracts against Candida species, including C. albicans, C. glabrata, C. tropicalis, using the agar-well diffusion method. Results: The minimal inhibitory concentrations (MICs) values of fruit and leaf extracts from Stachys acerosa leaf extracts ranged 3.12-12.5 mg/ml against the tested Candida. Conclusion: Based on the results, the ethanolic extracts of the selected plants exhibited antifungal potency against the tested fungi and could be used as an alternative natural antifungal agent and recommended to be used in the formulation of herbal mouthwash and toothpaste in future researches.

Biography :