Firoj A Tamboli and Harinath N More
Bharati Vidyapeeth, India
Posters & Accepted Abstracts: J Pharma Care Health Sys
Different extracts of Barleria gibsoni Dalz. (Acanthaceae) were screened for Anthelmintic activities using Indian earthworms (Pheretima posthuma). The ethanol extracts exhibited significant (p<0.01) anthelmintic activities compared with the control and other extracts. Albendazole was used as standards for anthelmintic activity. Anthelmintic activity of ethanol and aqueous extract of Barleria gibsoni stem bark was shown more significant paralysis and death as compared to standard drug albendazole at different concentration 5, 10, 15mg/ml, The ethanol extract at concentration 15mg /ml showed 89min for paralysis and 132min for death and standard drug 99min for paralysis and 119min for death. The aqueous extract did not show activity. Further investigations are however necessary to explore mechanisms of action involved in these pharmacological activities and constituents responsible for the activities.
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