Clinical & Experimental Cardiology
Open Access

Acute kidney injury after cardiac surgery - Can we do something about it?

20^th European Cardiology Conference

October 16-18, 2017 | Budapest, Hungary

Sophia Chew

Singapore General Hospital, Singapore

Scientific Tracks Abstracts: J Clin Exp Cardiolog

Abstract :

Acute kidney injury (AKI) is common, occurring in about one in three patients after cardiac surgery. It is associated with increased mortality, morbidity and healthcare costs. It is a multifactorial disorder and there is currently limited renoprotective mechanisms, hence prevention and early recognition of AKI is the focus of extensive clinical and basic science research. AKI risk models are useful for predicting acute renal failure requiring dialysis but are limited in non dialysis requiring AKI due to non-standardized definitions of AKI used, differing intraoperative variable, small cohorts and lack of external validation. Furthermore, all these models have been based on the western population which may not be valid in the AsiaPacific region. We developed and validated a risk model that utilized both preoperative and intraoperative variables to predict AKI after cardiac surgery in our local population. Similar to other studies, increased age, hypertension, eGFR less than 60 ml/ min, prolonged bypass time and use of intra-aortic balloon pump were risk factors for AKI. In addition, preoperative anemia, lowest haematocrit during bypass and intraoperative red blood cell transfusion are significant modifiable risk factors in our model. The risk score is easy to use, robust and allows for early detection of the patient at risk of AKI and institution of early management strategies. Our AKI risk model is the first developed for an Asian population and has high clinical utility given the large population of Chinese and Indians globally.

Biography :

Sophia Chew obtained her MBBS, MMed in Anaesthesia at National University of Singapore. She is a Fellow of the Australian and New Zealand College of Anaesthestists. She trained in Cardiac Anaesthesia at Duke University Medical Centre in the United States of America. She is the Director of Research in the Department of Anaesthesiology at Singapore General Hospital and Deputy Vice Chair of the Academic Clinical Program. She has published more than 25 papers in reputed journals and won numerous awards for abstract presentations both locally and internationally.