Endocrinology & Metabolic Syndrome
Open Access
ISSN: 2161-1017
ISSN: 2161-1017
Dr. Bennett Peter
James Cook University Hospital, United Kingdom
Scientific Tracks Abstracts: Endocrinol Metab Syndr
Background: Primary thyroid lymphoma (PTL) is a rare malignancy accounting for about 5% of all thyroid malignancies and less than 2% of extranodal lymphomas. The most common subtype of primary thyroid lymphoma is Diffuse B-cell lymphoma (DBCL). Patients and methods: A retrospective review was done of all patients diagnosed with thyroid lymphoma in our hospital from 2011 to 2021. Clinical, radiological, and pathological evaluations were conducted for all patients. Further follow up was done for these patients from diagnosis till date. Results: A total of eight patients were diagnosed with thyroid lymphoma in our hospital. Four were males and four were females. Mean age at diagnosis was 63 ± 32 years. Diagnosis was confirmed only with tissue histology. Six patients had stage IIE disease and two had stage IVE disease. Four patients had disease related mortality. Of the other four patients, two had chemotherapy (RCHOP) and one had local radiotherapy; all achieved complete remission, and the last one had hemithyroidectomy to relieve airway compression. Conclusion: Primary thyroid lymphoma is a rare malignancy of the thyroid gland. Poor prognostic factors include advanced stage and age at the time of diagnosis, the presence of compression symptoms, large tumor mass and presence of distant metastasis. Our knowledge of disease pathology, diagnosis, and management is still limited and more research is required.
Bennett Peter is a trust SHO in General surgery. He is interested in Endocrine and cancer research and keen on improving his knowledge on cancer surgery and treatment. He is interested in research writing and would like to contribute to the ever-expanding field of cancer research.