Toxicology Journal Scientific Journal | Peer Reviewed Journals
Journal of Drug Metabolism & Toxicology

Journal of Drug Metabolism & Toxicology
Open Access

ISSN: 2157-7609

Toxicology Journal Scientific Journal

Toxicology is a scientific discipline, overlapping with biologychemistrypharmacology, and medicine, that involves the study of the adverse effects of chemical substances on living organisms[1] and the practice of diagnosing and treating exposures to toxins and toxicants. The relationship between dose and its effects on the exposed organism is of high significance in toxicology. Factors that influence chemical toxicity include the dosage, duration of exposure (whether it is acute or chronic), route of exposure, species, age, sex, and environment. Toxicologists are experts on poisons and poisoning. There is a movement for evidence-based toxicology as part of the larger movement towards evidence-based practices.

The goal of toxicity assessment is to identify adverse effects of a substance. Adverse effects depend on two main factors: i) routes of exposure (oral, inhalation, or dermal) and ii) dose (duration and concentration of exposure). To explore dose, substances are tested in both acute and chronic models.Generally, different sets of experiments are conducted to determine whether a substance causes cancer and to examine other forms of toxicity.

Factors that influence chemical toxicity:

Dosage Both large single exposures (acute) and continuous small exposures (chronic) are studied. Route of exposure Ingestion, inhalation or skin absorption Other factors Species Age Sex Health Environment Individual characteristics

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