Immunohistochemistry

Immunohistochemistry is the most common application of immunostaining. It involves the process of selectively identifying antigens in cells of a tissue section by exploiting the principle of antibodies binding specifically to antigens in biological tissues. IHC takes its name from the roots "immuno" in reference to antibodies used in the procedure and histo meaning tissue. Albert Coons conceptualized and first implemented the procedure in 1941. Immunohistochemical staining is widely used in the diagnosis of abnormal cells such as those found in cancerous tumors. Specific molecular markers are characteristic of particular cellular events such as proliferation or cell death. Immunohistochemistry is also widely used in basic research to understand the distribution and localization of biomarkers and differentially expressed proteins in different parts of a biological tissue.

High Impact List of Articles

E3 Ligases in T Helper 2-mediated Pathogenesis
Anupama Sahoo, Beatrisa Lerman, Andrei Alekseev and Roza Nurieva
Review Article: Immunome Research
E3 Ligases in T Helper 2-mediated Pathogenesis
Anupama Sahoo, Beatrisa Lerman, Andrei Alekseev and Roza Nurieva
Review Article: Immunome Research
HLA mismatches and hematopoietic cell transplantation: structural simulations assess the impact of changes in pep-tide binding specificity on transplant outcome
Chen Yanover, Effie W. Petersdorf, Mari Malkki, Ted Gooley, Stephen Spellman, Andrea Velardi, Pe-ter Bardy, Alejandro Madrigal, Jean-Denis Bignon, Philip Bradley
Research Article: Immunome Research
HLA mismatches and hematopoietic cell transplantation: structural simulations assess the impact of changes in pep-tide binding specificity on transplant outcome
Chen Yanover, Effie W. Petersdorf, Mari Malkki, Ted Gooley, Stephen Spellman, Andrea Velardi, Pe-ter Bardy, Alejandro Madrigal, Jean-Denis Bignon, Philip Bradley
Research Article: Immunome Research
Identification of conformational B-cell Epitopes in an antigen from its primary sequence
Hifzur Rahman Ansari
Research Article: Immunome Research
Identification of conformational B-cell Epitopes in an antigen from its primary sequence
Hifzur Rahman Ansari
Research Article: Immunome Research
Evolution of a cluster of innate immune genes (b-defensins) along the ancestral lines of chicken and zebra finch
Robert Ekblom
Research Article: Immunome Research
Evolution of a cluster of innate immune genes (b-defensins) along the ancestral lines of chicken and zebra finch
Robert Ekblom
Research Article: Immunome Research
In silico identification of opossum cytokine genes suggests the complexity of the marsupial immune system rivals that of eutherian mammals
Emily SW Wong, Lauren J Young, Anthony T Papenfuss and Katherine Belov
Research Article: Immunome Research
In silico identification of opossum cytokine genes suggests the complexity of the marsupial immune system rivals that of eutherian mammals
Emily SW Wong, Lauren J Young, Anthony T Papenfuss and Katherine Belov
Research Article: Immunome Research

Conference Proceedings

Application of the theory of planned behaviour to vaccination of dogs against rabies in Abeokuta Ogun State, Nigeria
Awoyomi Olajoju J
Scientific Tracks Abstracts: Immunome Research
Application of the theory of planned behaviour to vaccination of dogs against rabies in Abeokuta Ogun State, Nigeria
Awoyomi Olajoju J
Scientific Tracks Abstracts: Immunome Research
Systemic autoimmune diseases
Zelalem Kiros
Posters & Accepted Abstracts: Immunome Research
Systemic autoimmune diseases
Zelalem Kiros
Posters & Accepted Abstracts: Immunome Research
New therapies for thyroid autoimmune diseases and Graves ophthalmopathy
Alessandro Antonelli, Poupak Fallahi, Silvia Martina Ferrari and Giusy Elia
Scientific Tracks Abstracts: Immunome Research
New therapies for thyroid autoimmune diseases and Graves ophthalmopathy
Alessandro Antonelli, Poupak Fallahi, Silvia Martina Ferrari and Giusy Elia
Scientific Tracks Abstracts: Immunome Research
The therapeutic P140 peptide, a new immunomodulating tool for lupus may have applications in other chronic inflammatory conditions
Sylviane Muller
Scientific Tracks Abstracts: Immunome Research
The therapeutic P140 peptide, a new immunomodulating tool for lupus may have applications in other chronic inflammatory conditions
Sylviane Muller
Scientific Tracks Abstracts: Immunome Research
Bioinks for 3D Bioprinting: A development parameters review
William George Whitford
Keynote: Immunome Research
Bioinks for 3D Bioprinting: A development parameters review
William George Whitford
Keynote: Immunome Research

Immunome Research
Open Access