Journal of Drug Metabolism & Toxicology
Open Access

Drug Metabolism Journals

Drug metabolism is that the chemical alteration of a drug by the body. Most drugs must undergo the liver, which is that the primary site for drug metabolism. Once within the liver, enzymes convert prodrugs to active metabolites or convert active drugs to inactive forms. The metabolism of pharmaceutical drugs is a crucial aspect of pharmacology and medicine. The enzymes of xenobiotic metabolism, particularly the glutathione S-transferases also are important in agriculture, since they'll produce resistance to pesticides and herbicides. Drug metabolism is split into three phases.