The Ovarian Metastases of Melanoma: Historical Cases
Journal of Women's Health Care

Journal of Women's Health Care
Open Access

ISSN: 2167-0420


Review Article - (2016) Volume 5, Issue 2

The Ovarian Metastases of Melanoma: Historical Cases

Wilson IB Onuigbo*
Department of Pathology, Medical Foundation and Clinic, Nigeria
*Corresponding Author: Wilson IB Onuigbo, Department of Pathology, Medical Foundation and Clinic, 8 Nsukka Lane, Enugu 40001, Nigeria, Tel: 2348037208680 Email:


It has been stressed that the history of a subject needs to be understood by the scientists of nowadays. Therefore, the parameters of the history of ovarian melanomatous deposits have been traced to their sources. The findings are interesting.

Keywords: Ovary; Cancer; Melanoma; Spread; History


On a great occasion, Kardinal made the point that it is important to facilitate the awareness of historical evidences. Therefore, this article sets out to document historical data on the very important female organ, the ovary [1].

Historical Texts

Battle [2] generalized on the “universal” deposition of melanoma in his 79-year-old patient, “including ovaries,” as he stated prominently. On the opposite ground of non-invasion, Coupland [3] cryptically came to “Ovaries shriveled.”

Legg [4] presented carefully, the history of a woman aged 30 years; she was admitted to St. Bartholomew’s Hospital under the care of Dr.Clark. At autopsy, the picture was clear, namely, “Both ovaries are the size of walnuts, and are formed of four or five new growths, without fluid contents.” Continuing, he mentioned that “parts of all the organs found to contain new growths were hardened in chronic acid.” Histological confirmation followed. This was also done in respect of the original eye growth.


The famous German pathologist, Julius Cohnheim, [5] was convinced that autopsies help in the understanding of natural phenomena. Accordingly, melanoma, which is characteristically pigmented, constitutes the best lesion for metastasis study. In the standard work on metastasis, Willis, [6] included a few historical cases of ovarian metastasis growths without much explanation. Here, pains were taken to expand the historical picture.


There is the axiom that “truths” need to be viewed from the vantage grounds of current perspectives [7]. Accordingly, on the bases of candid case reports, the present series demonstrated some 19th Century data on ovarian metastases. In sum, these cases add to the evidence missing from a recent historical survey of pigment biology [8] (Figure 1).


Figure 1: Excised specimen of an ovarian tumor.


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  3. Coupland S (1880) Primary diffuse malignant growth in the liver, in which the characters of sarcoma and cacinoma were apparent. Trans Path SocLond31: 130-135.
  4. Legg JW (1878)Melanotic sarcoma of the eyeball, secondary growths in the organs of the chest and belly, particularly in the liver. Trans Path SocLond 29:225-229.
  5. Cohnheim J (1889) Lectures on general pathology. The New Sydenham Society, Londonp: 14.
  6. Willis RA (1973)The spread of tumours in the human body. London: Butterworths p: 194.
  7. Moser KM (1987)Medical truths in historical perspective. Heart and Lung16:345-346.
  8. Nordlund JJ, Abdel-Malek ZA, Boissy RE (1989) Pigment cell biology: An historical review. J Invest Dermatol 92:53S-60S.
Citation: Onuigbo WIB (2016) The Ovarian Metastases of Melanoma: Historical Cases. J Women's Health Care 5:307.

Copyright: © 2016 Onuigbo WIB. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.