Th1, Th2 Serum Cytokines and Spleen White Pulp Changes Against Preliminary L. Major Vaccine Injection and Challenge With Live L. Major Promastigotes in Balb/C Mice

Latifynia A^1,2*, Gharagozlou MJ³, Mohebali M⁴, Hajjaran H⁴ and Khansari N¹

¹Department of Immunology, Faculty of medicine, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran

²Research Center for Immunodeficiencies, Children’s Medical Center Hospital, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran

³Department of Pathobiology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Islamic Republic of Iran

⁴Department of Parasitology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran

^*Corresponding Author: Latifynia A, Department of Immunology, Faculty of medicine, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran, Tel: +98-21-6643946 Email: