Research Article - (2014) Volume 0, Issue 0
Species Differences in the Pharmacokinetic Parameters of Cytochrome P450 Probe Substrates between Experimental Animals, such as Mice, Rats, Dogs, Monkeys, and Microminipigs, and Humans
- Sakai C1, Iwano S1, Yamazaki Y1, Ando A1, Nakane F2, Kouno M3, Yamazaki H4 and Miyamoto Y5*
- 1Toxicology and Pharmacokinetics Laboratories, Pharmaceutical Research Laboratories, Toray Industries, Inc, Kamakura, Kanagawa 248-8555, Japan
- 2Cmic Bioresearch Center Co., Ltd, Hokuto, Yamanashi 408-0044, Japan
- 3Kamakura Techno-Sience, Inc, Kamakura, Kanagawa 248-0036, Japan
- 4Laboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University, 3-3165 Higashi-tamagawa Gakuen, Machida, Tokyo, 194-8543, Japan
- 5Pharmaceutical Clinical Research Department, Head Office, Toray Industries, Inc, Urayasu, Chiba 279-8555, Japan
*Corresponding Author:
Miyamoto Y, Pharmaceutical Clinical Research Deptartment, Head Office, Toray Industries, Inc, Urayasu, Japan, Tel: +81-47-350-6729
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