Secondary Myelofibrosis in the Naturel History of JAK2, MPL and CALR Mutated Myeloproliferative Neoplasms

Jan Jacques Michiels^1*, Francisca Valster², Vincent Potter³, Katrien Schelfout³, Wilfried Schroyens⁴, Karel Fostier⁵, Timothy Devos⁶, Fibo Ten Kate⁶ and Hendrik De Raeve⁷

¹Goodheart Institute in Nature Medicine and Health, Erasmus Tower, Rotterdam, The Netherlands

²Department of Internal Medicine, BRAVIS Hospital, The Netherlands

³Department of Pathology, BRAVIS Hospital, The Netherlands

⁴Department of Hematology, University Hospital Antwerp, Edegem, Belgium

⁵Department of Hematology, University Hospital Brussels, Belgium

⁶Department of Hematology, University Hospital Leuven, Leuven, Belgium

⁷Department of Pathology, OLV Hospital Aalst OLV Ziekenhuis, Brussels, Belgium

^*Corresponding Author: Jan Jacques Michiels, Senior Internist and Investigator, Goodheart Institute and Foundation in Nature Medicine and Health, Erasmus Tower, Veenmos 13, 3069 AT Rotterdam, The Netherlands Email: