Prolonged Blood Circulation Time of Antimony in Dogs with Visceral Leishmaniasis from Liposomes with 175-nm Diameter

Erly Guilherme Azevedo¹, Raul Rio Ribeiro², Cláudio Dos Santos Ferreira³, Sydnei Magno Da Silva⁴, Dante Aligheiri Schettini⁵, Marilene Suzan Marques Michalick⁴, Cynthia Demicheli⁶ and Frédéric Frézard^1*

¹Department of Physiology and Biophysics, Institute of Biological Sciences, Federal University of Minas Gerais, Av Antonio Carlos 6627, Pampulha, 31270-901 Belo Horizonte, MG, Brazil

²Department of Veterinary Medicine, Center for Agricultural Sciences, Environmental and Biological Sciences, Federal University of Bahia Recôncavo, Campus of Cruz das Almas, Centre, 44380-000 Cruz das Almas, Bahia, Brazil

³Instituto of Exact Sciences and Technology, Forest Campus, University of Viçosa, LMG 818 km Highway 06, Forest 35690-000, MG, Brazil

⁴Departament of Parasitology, Institute of Biological Sciences, Federal University of Minas Gerais, Av Antonio Carlos 6627, Pampulha, 31270-901 Belo Horizonte, MG, Brazil

⁵West Campus Center Lindu, Federal University of Sao Joao del Rei, Av Sebastian 400 Gonçalves Coelho, Chanadour, Divinópolis 35501-296, MG, Brazil

⁶Department of Chemistry, Institute of Exact Sciences, Federal University of Minas Gerais, Av Antonio Carlos 6627, Pampulha, 31270-901 Belo Horizonte, MG, Brazil

^*Corresponding Author: Frédéric Frézard, Department of Physiology and Biophysics, Institute of Biological Sciences, Federal University of Minas Gerais, Av Antonio Carlos 6627, Pampulha, 31270-901 Belo Horizonte, MG, Brazil, Tel: +55 31 34092940, Fax: +55 31 34092924 Email: