Patients with Chronic Sarcoidosis have Reduced CD27+IgM+IgD+ Unswitched Memory B cells and an Expanded Population of Terminal Effector CD8+CD27-CD28- T cells

Adrian Heaps^1*, Veronica Varney², Shree Bhaskaran¹, Brian Ford¹, Angelina Mosley³, Ross Sadler⁴, Lisa Ayers⁴, Jane Evans², Amena Warner¹, Grant Hayman¹, Amolak Bansal¹ and Nazira Sumar¹

¹Department of Immunology, St Helier Hospital, Epsom and St Helier University Hospitals NHS Trust, Carshalton, Surrey, SM5 1AA, UK

²Department of Medicine, St Helier Hospital, Epsom and St Helier University Hospitals NHS Trust, Carshalton, Surrey, SM5 1AA, UK

³Department of Neuroinflammation, UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK

⁴Department of Clinical & Laboratory Immunology, Churchill Hospital, Oxford, OX37LJ, UK

^*Corresponding Author: Adrian Heaps, Department of Medical Biochemistry and Immunology, University Hospital of Wales, Cardiff, CF14 4XW, UK, Tel: 02920748352, Fax: 02920748383 Email: