LC-ESI-MS/MS Determination of GSK-199, A Novel Reversible PAD4 Inhibitor in Mice Plasma and its Application to a Pharmacokinetic Study in Mice

Gurulingappa Hallur¹, Buchi Reddy Purra¹, Jeyaraj Duraiswamy A¹, Suresh Sulochana P², Pavan Kumar Nagasuri VSP², Rudresh Gangaiah², Mohd Zainuddin², Sriram Rajagopal¹ and Ramesh Mullangi^1*

¹Medicinal Chemistry Department, Jubilant Biosys Limited, Industrial Suburb, Yeshwanthpur, Bangalore, Karnataka, India

²Drug Metabolism and Pharmacokinetics Department, Jubilant Biosys Limited, Industrial Suburb, Yeshwanthpur, Bangalore, Karnataka, India

^*Corresponding Author: Ramesh Mullangi, Medicinal Chemistry Department, Jubilant Biosys Limited, Industrial Suburb, Yeshwanthpur, Bangalore-560 022, Karnataka, India, Tel: +918066628339, Fax: +918066628333 Email: