Is Metabolic Activation of Topoisomerase II Poisons Important In The Mechanism Of Cytotoxicity?

Birandra K Sinha^* and Ronald P Mason

Immunity, Inflammation and Disease Laboratory, National Institutes of Environmental Health Sciences, NIH, Research Triangle, Park, North Carolina, USA

^*Corresponding Author: Birandra K Sinha, Immunity, Inflammation and Disease Laboratory, National Institutes of Environmental Health Sciences, NIH, Research Triangle, Park, North Carolina, USA, Tel: 919-541-4751 Email: