Imatinib Induces Growth Inhibition via Down Regulation of SKP2 in A431Human Skin Squamous Cell Carcinoma Cells

Sung-Hyun Kim^1,2, Hyo Jin Jeong¹, Yonghun Seong³, Song Park³, Jain Jeong³, Dong Joon Kim², In-Kyu Lee⁴, Zae Young Ryoo^3* and Myoung Ok Kim^5*

¹Institute of Life Science and Biotechnology, Kyungpook National University, 1370 Sankyuk-dong, Buk-ku, Daegu 702-701, Republic of Korea

²China-US (Henan) Hormel Cancer Institute, No.127 Dongming Road, Zhengzhou, Henan 450008, China

³School of Life Sciences and Biotechnology, KNU Creative Bio Research Group (BK21 plus project), Kyungpook National University, 1370 Sankyuk-dong, Buk-ku, Daegu 702-701, Korea

⁴Department of Internal Medicine, Kyungpook National University School of Medicine, Daegu, Republic of Korea

⁵School of Animal BT Sciences, Kyungpook National University, Sangju 742-711, Republic of Korea

^*Corresponding Author(s): Zae Young Ryoo, School of Life Sciences and Biotechnology, BK21 Plus KNU Creative Bioresearch Group, Kyungpook National University, 80 Daehakro, Bukgu, Daegu, 41566, Republic of Korea, Tel: + 82- 53-943-6925 Email: Myoung Ok Kim, School of Animal BT Sciences, Kyungpook National University, 2559, Gyeongsang- Daero, Sangju-si, Gyeongsangbuk-do, Republic of Korea, Tel: +82-54-530-1234 Email: