Genotype Distribution of Dihydrofolatereductase Variants and their Role in Disease Susceptibility to Acute Lymphoblastic Leukemia in Indian Population: An Experimental and Computational Analysis

Sunitha Kodidela^1*, Suresh Chandra Pradhan¹, Jayaraman Muthukumaran², Biswajit Dubashi³, Teresa Santos-Silva² and Debdatta Basu⁴

¹Department of Pharmacology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India

²UCIBIO@REQUIMTE, Departament of Chemistry, Faculty of Science and Technology, New University of Lisbon, 2829-516 Caparica, Portugal

³Department of Medical Oncology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India

⁴Department of Pathology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India

^*Corresponding Author: Sunitha Kodidela, Department of Pharmacology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India, Tel: +917639656035 Email: