Exposure to Nicotine in Adult, but not Adolescent, Rats Increases Alcohol Self-Administration in Adulthood

Paula C Bianchi^1,2#, Fabio C Cruz^3,4#, Paulo E Carneiro-de-Oliveira^1,2, Tarciso T Miguel⁵, Marcelo T Marin^1,2, Ricardo L Nunes-de-Souza^1,2, Cleopatra S Planeta^1,2 and Rodrigo M Leão^1,2,3*

¹Laboratory of Pharmacology, São Paulo State University (Unesp), School of Pharmaceutical Sciences, Araraquara, SP, Brazil

²Joint Graduate Program in Physiological Sciences, UFSCar/UNESP, Araraquara, São Paulo, Brazil

³Departamento de Biorregulacao, Instituto de Ciências da Saúde, Universidade Federal da Bahia, Salvador, BA 40110-902, Brazil

⁴Pharmacology Department, São Paulo Federal University, UNIFESP, Brazil

⁵Biomedical Sciences Institute, Universidade Federal de Uberlândia, Uberlândia, Minas Gerais, Brazil

^#Contributed equally to this work

^*Corresponding Author: Rodrigo M Leão, Departamento de Biorregulacao, Instituto de Ciências da Saúde, Universidade Federal da Bahia, Av. Reitor Miguel Calmon, S/n, Vale Do Canela, Salvador, BA 40110-902, Brazil, Tel: 55-71- 3283 8885, Fax: 55-71- 3283 8894 Email: