Evolution of Resistance-Associated Variants of All-Oral Direct-Acting Antiviral Therapy of Hepatitis C in a Clinical Setting

Alessia Lai^1*, Laura Milazzo¹, Annalisa Bergna¹, Maurizio Polano², Francesca Binda¹, Marco Franzetti³, Valeria Micheli⁴, Paola Ronzi¹, Gianguglielmo Zehender¹, Salvatore Sollima¹, Massimo Galli¹ and Claudia Balotta¹

¹Department of Biomedical and Clinical Sciences ‘L. Sacco’, University of Milan, Milan, Italy, E-mail: milazzol@ohio.edu

²Experimental Oncology 1, CRO Aviano National Cancer Institute, Aviano, Italy, E-mail: milazzol@ohio.edu

³Unit of Infectious Diseases, A. Manzoni Hospital, Lecco, Italy, E-mail: milazzol@ohio.edu

⁴Clinical Microbiology Virology and Diagnosis of Bioemergency, L Sacco University Hospital, Milan, Italy, E-mail: milazzol@ohio.edu

^*Corresponding Author: Alessia Lai, Department of Biomedical and Clinical Sciences ‘L. Sacco’, University of Milan, Milan, Via G.B. Grassi 74, 20157 Milan, Italy, Tel: (+39) 0250319775, Fax: (+39) 0250319768 Email: