GET THE APP

Journal of Women's Health Care

Journal of Women's Health Care
Open Access

ISSN: 2167-0420

Rapid Communication - (2024)Volume 13, Issue 3

Debating Bilateral Oophorectomy: Perspectives and Considerations

Laz Conley*
 
*Correspondence: Laz Conley, Department of Gynecology and obstetrics of Parma, University of Parma, Italy, Email:

Author info »

Bilateral oophorectomy, the surgical removal of both ovaries, is a medical procedure that has sparked considerable debate among healthcare professionals, researchers, and women considering the surgery. This contentious topic involves a complex interplay of medical necessity, risk assessment, and patient autonomy. In this article, we explore the various perspectives and considerations surrounding bilateral oophorectomy [1].

Understanding Bilateral Oophorectomy

Bilateral oophorectomy is performed for various medical reasons, including the prevention or treatment of ovarian cancer, management of hormone-related conditions such as endometriosis or polycystic ovary syndrome (PCOS), and reduction of ovarian hormone production in hormone-sensitive cancers like breast cancer [2-4].

Perspectives in Favor of Bilateral Oophorectomy

Proponents of bilateral oophorectomy often highlight its role in reducing the risk of ovarian cancer, a disease notorious for its late-stage diagnosis and poor prognosis. For women with a strong family history of ovarian cancer or carriers of genetic mutations such as BRCA1 and BRCA2, prophylactic bilateral oophorectomy can significantly decrease the likelihood of developing this deadly cancer.

Furthermore, in cases where hormone-related conditions like endometriosis or PCOS severely impact a woman's quality of life and conventional treatments have proven ineffective, bilateral oophorectomy may offer relief from symptoms and improve overall well-being [5].

Considerations and Controversies

Despite its potential benefits, bilateral oophorectomy is not without controversy and considerations. One of the primary concerns revolves around the abrupt induction of surgical menopause, which can lead to a range of physical and psychological symptoms including hot flashes, vaginal dryness, mood swings, and increased risk of osteoporosis and cardiovascular disease [6].

Moreover, the decision to undergo bilateral oophorectomy involves a delicate balance between cancer risk reduction and the preservation of hormonal balance. Estrogen deprivation resulting from oophorectomy may have long-term implications for bone health, cognitive function, and cardiovascular health, prompting some experts to advocate for hormone replacement therapy (HRT) to mitigate these risks [7].

Additionally, for women of reproductive age, bilateral oophorectomy eliminates the possibility of conceiving biologically related children and necessitates consideration of fertility preservation options such as oocyte cryopreservation or embryo banking prior to surgery [8].

In the realm of women's health, bilateral oophorectomy remains a subject of intense debate and deliberation. While it offers a definitive solution for reducing ovarian cancer risk and managing certain hormone-related conditions, it also poses significant challenges and considerations, particularly regarding the impact of surgical menopause and long-term hormone replacement therapy [9].

Ultimately, the decision to undergo bilateral oophorectomy should be informed by a comprehensive discussion between patients and healthcare providers, weighing the potential benefits, risks, and personal preferences. By fostering open dialogue and ensuring informed consent, individuals can make empowered decisions that align with their health needs and values [10].

References

  1. Koch T, Therming Jørgensen J, Christensen J, Duun Henriksen AK, Priskorn L, Kildevæld Simonsen M, et al. Bilateral oophorectomy and rate of colorectal cancer: A prospective cohort study. Int J Cancer. 2022;150(1):38-46.
  2. Indexed at, Google Scholar, Cross Ref

  3. Rocca WA, Mielke MM, Gazzuola Rocca L, Stewart EA. Premature or early bilateral oophorectomy: a 2021 update. Climacteric. 2021;24(5):466-73.
  4. Indexed at, Google Scholar, Cross Ref

  5. Rocca WA, Smith CY, Rocca LG, Savica R, Mielke MM. Association of Premenopausal Bilateral Oophorectomy With Parkinsonism and Parkinson Disease. JAMA Netw Open. 2022;5(10):e2238663.
  6. Indexed at, Google Scholar, Cross Ref

  7. Olesen CS, Koch T, Uldbjerg CS, Gregersen LS, Christensen J, Dehlendorff C, et al. Cardiovascular mortality after bilateral oophorectomy: a prospective cohort study. Menopause. 2022;29(1):28-34.
  8. Indexed at, Google Scholar, Cross Ref

  9. Lovett SM, Sandler DP, O’Brien KM. Hysterectomy, bilateral oophorectomy, and breast cancer risk in a racially diverse prospective cohort study. J Natl Cancer Inst. 2023;115(6):662-70.
  10. Indexed at, Google Scholar, Cross Ref

  11. Kapoor E, Faubion SS, Rocca LG, Mielke MM, Smith CY, Rocca WA. Trajectories of metabolic parameters after bilateral oophorectomy in premenopausal women. Maturitas. 2022;165:38-46.
  12. Indexed at, Google Scholar, Cross Ref

  13. Scime NV, Brown HK, Metcalfe A, Simpson AN, Brennand EA. Bilateral salpingo-oophorectomy at the time of benign hysterectomy among females with disabilities: a population-based cross-sectional study. Am J Obstet Gynecol. 2023;229(6):658-e1.
  14. Indexed at, Google Scholar, Cross Ref

  15. Song M, Nelson RA, Kruper L, Mortimer J, Luo J, Jung SY, et al. Bilateral oophorectomy and colorectal cancer incidence and mortality in the Women's Health Initiative. Cancer epidemiology, biomarkers & prevention. 2023;32(11):1668-71.
  16. Indexed at, Google Scholar, Cross Ref

  17. Cusimano MC, Moineddin R, Chiu M, Ferguson SE, Aktar S, Liu N, et al. Practice variation in bilateral salpingo-oophorectomy at benign abdominal hysterectomy: a population-based study. Am J Obstet Gynecol. 2021;224(6):585-e1.
  18. Indexed at, Google Scholar, Cross Ref

  19. Iancu AM, Murji A, Chow O, Shapiro J, Cipolla A, Shirreff L. Avoidable bilateral salpingo-oophorectomy at hysterectomy: a large retrospective study. Menopause. 2022;29(5):523-30.
  20. Indexed at, Google Scholar, Cross Ref

Author Info

Laz Conley*
 
Department of Gynecology and obstetrics of Parma, University of Parma, Parma, Italy
 

Citation: Conley L, (2024). Debating Bilateral Oophorectomy: Perspectives and Considerations. J Women's Health Care. 13(3):718.

Received: 26-Feb-2024, Manuscript No. 30021; Editor assigned: 29-Feb-2024, Pre QC No. 30021; Reviewed: 11-Mar-2024, QC No. 30021; Revised: 16-Mar-2024, Manuscript No. 30021; Published: 25-Mar-2024 , DOI: 10.35248/2167-0420.24.13. 718

Copyright: © 2024 Conley L. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited

Top