Journal of Drug Metabolism & Toxicology

Journal of Drug Metabolism & Toxicology
Open Access

ISSN: 2157-7609

Research Article - (2016) Volume 0, Issue 0

Comparative Metabolism of Batracylin (NSC 320846) and Nacetylbatracylin (NSC 611001) Using Human, Dog, and Rat Preparations In Vitro

Joseph M Covey1*#, Joel M Reid2#, Sarah A Buhrow2, Mary Kuffel2, Chad Walden2, Holger Behrsing3,4 and Matthew M Ames2
1Toxicology and Pharmacology Branch, Developmental Therapeutics Program, DCTD, NCI, Rockville, USA
2Department of Oncology, Division of Oncology Research, Mayo Clinic and Foundation Rochester, MN, USA
3Laboratory for Investigative Toxicology, Applied/Developmental Research Directorate, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, USA
4Institute for In Vitro Sciences, 30 West Watkins Mill Road, Gaithersburg, USA
#Contributed equally to this work
*Corresponding Author: Joseph M Covey, PhD, Toxicology and Pharmacology Branch, Developmental Therapeutics Program Division of Cancer Treatment and Diagnosis, National Cancer Institute, National Institutes of Health, 9609 Medical Center Drive, Bethesda, Maryland 20892, USA, Tel: 240-276-5912 Email:

Abstract