International Journal of Physical Medicine & Rehabilitation

International Journal of Physical Medicine & Rehabilitation
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ISSN: 2329-9096

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Letter to Editor - (2021)Volume 9, Issue 2

Clinico-Pathological Aspects of Spinal Nerve Root Entrapment

Naglaa Hussein*
 
*Correspondence: Naglaa Hussein, Department of Physical Medicine and Rehabilitation, Albert Einstein College of Medicine NY and, Alexandria, Egypt, Tel: 3474792686, Email:

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Description

The patterns of the clinical presentation of spinal nerve root entrapment are subject of wide variability [1-3]. Although the sensory presentation patterns dominate different patterns of clinical presentation, other patterns namely; motor or sensorimotor patterns are also encountered [1,4].

This variability in the pattern of clinical presentation is thought to be reflection of the pathogenetic mechanisms involved in spinal nerve root entrapment.

Literature review revealed that the correlation between the patterns of clinical presentations and the pathophysiological mechanisms of spinal nerve root entrapment were not adequately considered. Many questions in this context could be raised for instance how far the degree and/ or the duration of nerve root compression and the resulting pathological changes affect the clinical expression of the disease.

As the sensory presentation is the most frequently encountered pattern of clinical presentations among cases of spinal nerve root entrapment [1-4]. Clinico-pathological analysis of sensory presentations is related to the higher vulnerability of sensory neurons of dorsal root ganglia to ischemia and compression [5-15] as compared to motor root. Furthermore, the regenerative potential of sensory neurons is less than that of the motor neurons [16-18].

The quality of the sensory manifestations i.e. numbness, paresthesia and pain could not be absolutely correlated to the degree of nerve root compression [5,15].

As numbness a major symptom in nerve root compression, was proved in vivo study to be involved with ischemia and not mechanical nerve fiber deformation [5,19].

The severity and the degree of spinal nerve root compression directly influence the course of the clinical manifestations of the condition. With low compression for example, 30-50 mm hg the consequentpathological changes of the nerve root will be reversible. If the compression is released after single trauma [5]. Hence its corresponding clinical manifestations.

Whereas, with sustained high pressure or repeated pressure, there will be different kinds of nerve lesions either segmental demyelination or in cases of severe trauma axonal degeneration [5]. This will be reflected on the extent of severity and potential for recovery of the clinical manifestations [5].

The occasional presence of different clinical manifestations in the same patient could be correlated to the presence of different kinds of pathology in individual nerve fibers contained in the spinal nerve root. In this regard, the presence of muscle weakness or sensory deficit that represent loss of nerve function could be associated with state of hyperexcitability of nerve tissue that gives rise to positive symptoms that is; pain, paresthesia and possibly muscle fasciculation from the respective nerves. This condition means that nerve fibers, although have decreased conduction velocity at the site of injury, still being hypersensitive to further mechanical stimulus at the injured segment [5].

The mode of spinal nerve root compression also affects the clinical presentation of the disease 5 and the direct application of this fact is seen when the lumbar nerve roots in the cauda equina are compressed in association with spinal stenosis, the pressure is distributed in circumferential manner around the roots at a slow rate [5].

This situation is compared with the mechanics when a dorsolateral disc herniation induced displacement of nerve root with unilateral compression and increased intraneural tension. The different clinical symptoms induced by nerve root compression in association with spinal stenosis and herniated nucleus pulposus respectively may in part be a consequence of the different kinds of nerve tissue deformation induced in these two conditions [5].

References

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Author Info

Naglaa Hussein*
 
Department of Physical Medicine and Rehabilitation, Albert Einstein College of Medicine NY and, Alexandria, Egypt
 

Citation: Hussein N (2021) Clinico-Pathological Aspects of Spinal Nerve Root Entrapment. Int J Phys Med Rehabil. 9:592

Received: 23-Feb-2021 Accepted: 09-Mar-2021 Published: 16-Mar-2021 , DOI: 10.35248/2329-9096.21.9.e002

Copyright: © 2021 Hussein N. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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