Autosomal Dominant Hereditary Essential Thrombocythemia due to a Gain of Function Mutation in the Thrombopoietin (TPO) and JAK2 Gene as the Cause of Congenital Aspirin-Responsive Sticky Platelet Syndrome: Personal Experiences and Review of the Litera

Jan Jacques Michiels^1*, Jan Stasko², Peter Kubish², Achille Pich³ and Hendrik De Raeve⁴

¹Multidisciplinary Internist & Investigator, Goodheart Institute & Foundation, Rotterdam and International Collaborations and Research on Myeloproliferative neoplasms (ICAR.MPN), Erasmus Tower, Veenmos 13 3069 AT Rotterdam, The Netherlands

²Department of Hematology, University Hospital Martin, Jessenius Faculty of Medicine in Martin of the Comenius University in Bratislava, Slovakia

³Department of Molecular Biotechnology and Health Sciences, Section of Pathology, University of Turin, Via Santena 7, I-10126 Torino, Italy

⁴Department of Pathology, OLV Hospital Aalst and University Hospital of Brussels, Laarbeeklaan 101, B-1090, Brussels, Belgium

^*Corresponding Author: Jan Jacques Michiels, Multidisciplinary Internist & Investigator, Goodheart Institute & Foundation, Rotterdam and International Collaborations and Research on Myeloproliferative neoplasms (ICAR.MPN), Erasmus Tower, Veenmos 13 3069 AT Rotterdam, The Netherlands Email: