Absorption, Distribution and Excretion Pattern of Oral and Transdermal Donepezil Hydrochloride after Single and Repeated Administration to the Rat

Susan R. Meier-Davis^1*, Marie-Eve Rodrigue², Masahiro Yamaji¹, Yoshiko Katori-Stowell¹, Jianye Wen¹, Fatima M. Arjmand¹, Jutaro Shudo¹ and Tetsuto Nagata¹

¹Teikoku Pharma, Inc, USA

²Charles River Laboratories, USA

^*Corresponding Author: Susan R. Meier-Davis, Teikoku Pharma USA, Inc., 1718 Ringwood Avenue, San Jose, CA 95131, USA, Tel: 408-501-1829, Fax: 408-501-1929 Email: