A Potential Administration-time Dependent Effect of Bevacizumab in Improving Overall Survival and Increasing Metastasis in Metastatic Colorectal Cancer

Bei Zhang^1,2#, Wenzhuo He^1,2#, Feifei Zhou³, Guifang Guo^1,2, Chang Jiang^1,2, Chenxi Yin^1,2, Xuxian Chen^1,2, Huijuan Qiu^1,2, Yuming Rong^1,2 and Liangping Xia^1,2*

¹State Key Laboratory of Oncology in South China, Sun Yat-sen University Cancer Center, Guangzhou, P.R. China

²VIP Region, Sun Yat-sen University Cancer Center, Guangzhou, P.R. China

³Tumor Center, The Foshan First People’s Hospital, Foshan, P.R. China

^#Contributed equally to this work

^*Corresponding Author: Liangping Xia, State Key Laboratory of Oncology in South China, Sun Yat-sen University Cancer Center, Guangzhou, P.R. China, Tel: +8620-87343107, Fax: +86-20-87343392 Email: