Journal of Clinical & Experimental Dermatology Research

Journal of Clinical & Experimental Dermatology Research
Open Access

ISSN: 2155-9554

Clinical image - (2019)Volume 10, Issue 6

A Giant Buschke-Löwenstein Tumor

Sara Mai1*, Salima Baya2, Safae Maouini1, Kaoutar Znati3, Jawad Hafidi2, Abdellah Abbassi2 and Karima Senouchi1
 
*Correspondence: Sara Mai, Department of Dermatology, University Hospital Ibn Siba, Rabat, Morocco, Tel: +212625104836, Email:

Author info »

Abstract

A 70-year-old man with no notable medical history presented to our department with a huge tumor on his pubic area that had been evolving for over 20 years causing itching and foul smelling discharge. Physical examination revealed a cauliflower-like voluminous tumor on the patient’s pubis with extension to the penoscrotal area and the lower abdomen (Figure 1).

Clinical Image

A 70-year-old man with no notable medical history presented to our department with a huge tumor on his pubic area that had been evolving for over 20 years causing itching and foul smelling discharge. Physical examination revealed a cauliflower-like voluminous tumor on the patient’s pubis with extension to the penoscrotal area and the lower abdomen (Figure 1). A giant condyloma acuminate was suspected and extensive surgical excision was performed. Histopathological examination revealed hyperkeratosis, acanthosis, marked papillomatosis and koilocytes; confirming the diagnosis of Buschke-Löwenstein tumor (Figure 2). There were no features of malignant transformation [1-3].

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Figure 1. Patient’s pubis with extension to the penoscrotal area and the lower abdomen.

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Figure 2. Diagnosis of Buschke-Löwenstein tumor.

Buschke-Löwenstein tumor or giant condyloma acuminatum is a rare sexually transmitted disease, caused by human papillomavirus; genotypes 6 and 11 in most cases. It’s incidence of about 0.1% in the general population, predominantly young men. Clinically it presents as a large, cauliflower-like tumor with papillomatous or verrucous surface. Radical excision of the entire lesion with histopathological examination of the whole lesions is recommended to confirm the diagnosis and detect a malignant transformation. Post-operative surveillance is necessary to identify potential recurrences [4,5].

Funding

Nil.

Conflict of Interest

The authors declare that they have no competing interest.

References

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  2. Chu QD, Vezeridis MP, Libbey NP, Wanebo HJ. Giant condyloma acuminatum (Buschke-Lowenstein tumor) of the anorectal and perianal regions. Analysis of 42 cases. Dis Colon Rectum. 1994;37:950-957.
  3. Heinzerling LM, Kempf W, Kamarashev J, Hafner J, Nestle FO. Treatment of verrucous carcinoma with imiquimod and CO2 laser ablation. Dermatology. 2003;207:119-122.
  4. Creasman C, Haas PA, Fox TA Jr, Balazs M. Malignant transformation of anorectal giant condyloma acuminatum (Buschke-Lowenstein tumor) Dis Colon Rectum. 1989;32:481-487.
  5. Geusau A, Heinz-Peer G, Volc-Platzer B, Stingl G, Kirnbauer R. Regression of deeply infiltrating giant condyloma (Buschke-Löwenstein tumor) following long-term intralesional interferon alfa therapy. Arch Dermatol. 2000;136:707-710.