Department of Biochemistry and Molecular Biology
Pennsylvania State University, USA
Dr. Wang received a bachelor degree in Biochemistry in Shandong University in 1994 and obtained a diploma in Developmental Biology from Shanghai Institute of Cell Biology of the Chinese Academy of Sciences in 1997. He then moved to the US and received a Ph.D. degree in Molecular, Cellular and Developmental Biology at the Iowa State University in 2001. In his Ph.D. thesis work, Dr. Wang found that the Drosophila JIL-1 kinase regulates dosage compensation of the male X-chromosome by phosphorylating histone H3 serine 10site. His interest has been in chromatin biology and histone modifications ever since. He joined Dr. C. David Allis as a postdoc to polish himself as a “histone code” miner for 4 years. In his own lab at Penn State, Dr. Wang has been studying histone and protein Arg citrullination among other endeavors. Most recently, he is developing anticancer drugs to turn on tumor suppressor genes.
Epigenetic histone modifications in cell differentiation and cancer