Department of Medicine
Uniformed Services University of the Health Sciences, Bethesda, USA
Xiaoming Zhou is an Associate Professor The Department of Medicine, School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, USA. He received his M.D., Ph.D. in Physiology, The Department of Physiology, College of Medicine, University of Florida, Gainesville, FL, USA. He was honoured by Research Recognition Award, American Physiological Society Renal Section, Washington, DC, April 20, 2004, Trainee Investigator Award, American Society for Clinical Investigation, Baltimore, MD, May 4, 1992, Excellence in Renal Research Award, The American Physiological Society, Anaheim, CA, April 8, 1992.
I have studied the signaling pathways mediating the effects of high levels of NaCl (hypertonicity) in cell culture and the kidney medulla, which is normally exposed to a hypertonic environment for more than a decade. Recent discovery of the critical roles of high levels of NaCl in inducing Th17 cell polarization and high salt diet in exacerbation of multiple sclerosis and its animal model experimental autoimmune encephalomyelitis (EAE) has attracted me to study how salt contributes to the pathogenesis of multiple sclerosis and EAE, which may lead to novel therapeutics for treatment of multiple sclerosis. This project has been funded by a grant from the national multiple sclerosis society.