Tin-Lap Lee, PhD
Laboratory of Clinical Genomics, National Institutes of Child Health and Human Development
Dr. Tin-Lap Lee is a Staff Scientist at the Laboratory of Clinical Genomics, National Institutes of Child Health and Human Development (NICHD) and Project Coordinator at National Center for Biotechnology Information (NCBI).
His research interests include developmental biology and biomedical informatics. Using male germ cells as model system, he identified genes and molecular networks that govern cellular differentiation and proliferation, which are fundamental process leading to normal or disease states. He also developed algorithms and databases to facilitate genomic data mining, including SAGEcluster, GermSAGE, GonadSAGE and TileMapper. Recently his group has identified a long non-coding RNA candidate known as Spga-lncRNA1/2 that controls Spermatogonial Stem Cell (SSC) differentiation. His works have been recognized NIH Merit Award, The NIH Fellows Award for Research Excellence and young scholar awards from American Association for Cancer Research and American Nanomedicine Society.
Genomic regulations of non-coding RNAs in spermatogonial stem cells
Developmental and genome biology
Nanotoxicology and nanomedicine
Systems biology modeling and algorithm development