Journal of Developing Drugs
Open Access

Ronald R Burnette

Biography

Ron received his B.S. degree (1971) in electrical engineering from the University of California-Irvine, M.S. degree (1973) in electrical engineering from Stanford University, and Pharm.D. (1979) and Ph.D. (1982) degrees in pharmaceutical chemistry from the University of California-San Francisco. He joined the Wisconsin faculty in 1982.

Research Interest

At the whole organism level (animal and human), our research group is interested in developing computer algorithms, using the principles obtained from pharmacokinetics, pharmacodynamics and pharmacogenomics, in order to optimize drug delivery and to understand drug interactions.
       At the molecular level, the basic premise underlying our research is that one can combine experimental data, such as that obtained from spectroscopic techniques and X-ray crystallography, in a synergistic manner with computational chemistry to determine molecular structure and to understand intermolecular and intramolecular interactions. This, in turn, provides the basis for beginning to understand drug delivery systems at a more fundamental level. More precisely these investigations provide a mechanism by which one can start to predict how specific molecular changes will alter a drug delivery system at both the structural and energetic level.