Professor, Department of Internal Medicine II
Teaching Hospital of the Goethe University of Frankfurt/Main, Germany, Germany
He is born April 15, 1944 in Gera, a town in East Germany, and studied medicine at the universities of Munich and Marburg, where he received his M.D. and finished his inaugural thesis. He is internist with subspecialty in gastroenterology and hepatology and professor of Medicine at the Heinrich Heine University of Düsseldorf/ Germany. His scientific and clinical interest in hepatotoxicity started as resident at the Department of Pathology, University of Marburg/Germany, with following focus on alcoholic liver disease and biochemical studies as resident at the Bronx VA Hospital/Mount Sinai Hospital in New York with Professor Charles S. Lieber during 1972-1975, appreciating living in NYC and excellent local research conditions. More specifically, here he solubilized the hepatic microsomal ethanol oxidizing system and isolated it from the other alcohol metabolizing enzymes alcohol dehydrogenase and catalase by DEAE column chromatography. Other studies included the area of cytochrome P450 and various microsomal enzymes. Back in Germany, he had positions as resident and professor at the Department of Medicine, section of Gastroenterology, Hepatology, and infection at the Heinrich Heine University in Düsseldorf/ Germany. Here he finished his habilitation thesis and received a highly prized university award for his outstanding research. He undertook clinical and experimental studies focusing on hepatotoxicity by alcohol, hydrocarbons, and drugs. When he was offered a chief position in 1987 and was appointed as director of the Medical Department II, City Hospital Hanau, Teaching Hospital of the Johann Wolfgang Goethe University Frankfurt/Main, Germany, he increasingly became interested in herbal hepatotoxicity. He is author or coauthor of more than 250 publications in English, including book chapters and books. He was nominated associate editor of Annals of Hepatology and is member of the editorial board of many other journals.
His research interest includes Clinical hepatology, DILI, HILI, RUCAM, drugs, herbs, alcohol and aliphatic halogenated hydrocarbons, etc.