Professor, Department of Molecular Bioengineering
Imperial College of London, UK
Professor Krams holds a Chair in Molecular Bioengineering at Imperial College, London. Prior to joining Imperial College he worked as Associate Professor in the department Bioengineering, Thoraxcentre Rotterdam, the Netherlands and as associate professor/chair in the department of Medical Physics, Free University in Amsterdam. He received his Medical Degree and Ph.D. from the Free University, Amsterdam in 1989. His research is focussed on the molecular mechanism underlying biomechanical stimuli. To that end he uses a combination of engineering techniques (imaging, systems biology and synthetic biology) and molecular techniques (high throughput, qPCR, life cell imaging) to study the interaction of gene expression and shear stress and wall stress on cells in culture and in whole animals. It has led to the development of new devices for patient and experimental studies and to the development of new analysis techniques for images obtained by microscopes. The work that will be started up in London consists of imaging of animals and application of system biology and mult-scale modelling to vascular biology.