Monath Sanjaya Kuruppu
Department of Pharmacology and Biochemistry
Monash University, Australia
I obtained my PhD in Pharmacology from Monash University in Australia. My research focussed on the pharmacological characterisation of peptide neurotoxins from Australian and Papua New Guinean snake venoms. I also examined the efficacy of commercially available antivenoms in neutralising the effect(s) of these toxins. My postdoctoral training was conducted in the Department of Biochemistry & Molecular Biology (Monash University). The research conducted focused on proteases that play a key role in the cardiovascular system and their substrates. My current research focuses on understanding the role of above mentioned proteases in the pathogenesis of cardiovascular diseases, with a particular emphasis on clinical translation.
Identification of specific inhibitors of Endothelin Converting Enzyme-1 from natural sources such as snake venoms, and determining the cross reactivity of locally produced antivenoms with toxins from snakes in different geographical regions.