Husam Abu Soud
Associate Professor, Department of Gynecology and Obstetrics
Wayne State University, USA
Dr. Husam Abu-Soud is working as an Associate Professor in the department of Gynecology and Obstetrics from Wayne State University.
Long-term objective is to understand the mechanisms by which oxidative damage contributes to the pathogenesis of inflammatory diseases. Four major research projects are currently under investigation:
Structure-function studies of the three isoforms of nitric oxide synthase and their regulation in vivo;
The role of mammalian peroxidases and nitric oxide synthases in promoting oxidative stress and their potential involvement in the disease state;
Identification of potent inhibitors for mammalian peroxidases and
The role of reactive oxygen and nitrogen species on oocyte aging. These projects involve the utilization of state of the art analytical methods which include enzyme purification, expression cloning, site-directed mutagenesis, and methods to study protein spectroscopy including EPR, HPLC, stopped-flow and rapid quench.