Associate Professor, Department of Biology
ï»¿Villanova University, USA
He obtained his BS Biology and MS degrees Organic Chemistry from Jammu University, Jammu & Kashmir State, India and PhD 1987 from All India Institute of Medical Sciences, New Delhi,India Immunology. He authored about 22 publications that inclide articles and reviews. He received All India Institute of Medical Sciences Fellowship Award India for PhD studies and Arthritis Investigator Award from Arthritis Foundation.
Cell and Molecular Immunology. My research interest encompasses the field of lymphocyte biology. A major goal of my research is to understand mechanisms underlying regulation of CD4+ T lymphocyte responses to protein antigens. Focus of research in my laboratory is on a set of glycosylphosphatidyl-inositol (GPI)-anchored proteins housed in membrane rafts. Membrane rafts are 10-200 nanometer size domains on the plasma membrane. These membrane entities are enriched in sphingolipids, cholesterol, GPI-anchored proteins and a variety of other signaling molecules. Membrane rafts have been implicated in spatiotemporal regulation of signaling from the membrane to cell interior. My laboratory has developed methods that will allow us to examine membrane rafts on single-nanodomain basis and investigate their spatial organization during CD4+ T cell activation and differentiation.